Publications & Highlights
Journal of the American Chemical Society (JACS)
J-H. Lee, Z. Cheglakov, J. Yi, T. M. Cronin, K. J. Gibson, B. Tian, and Y. Weizmann. Plasmonic Photothermal Gold Bipyramid Nanoreactors for Ultrafast Real-Time Bioassays. J. Am. Chem. Soc., 139, 8054-8057 (2017)
Highlighted in JACS Spotlights
"Nucleic acid amplification (NAA) methods, which create many copies of a small sample of DNA for biological and biomedical research and applications, rely on heating the sample or alternating cycles of heating and cooling. However, the instrumentation used to meet these temperature requirements is typically expensive, time-consuming, heavy, and energetically draining. Yossi Weizmann and colleagues report a novel nanoparticle-based technique that achieves rapid and low-energy thermocycling for uniform and steady heating for various NAA strategies"
Highlights in Nature Methods:
"Ultrafast thermal cycling"
"The polymerase chain reaction (PCR) is ubiquitous in biological research laboratories, and substantial technological advances have improved our ability to control the speed and accuracy of this important process. The majority of PCRs are carried out on devices with heating blocks that heat and cool the reactions over multiple cycles. Although these devices work well, the time they take to heat and cool samples can be substantial. Lee et al. present an alternative approach for cost-effective, ultrafast thermal cycling"
Nat. Methods 14, 653 (2017);
Awards & Media
June 2016 Sensona (IR-PCR) wins The Polsky Center Innovation Fund Award
From the Polsky Center report: "IR-PCR Formerly Nucleic Acid Detection, Infrared Polymerase Chain Reaction methods represent valuable and important tools for chemists, biologists, and medical scientists. IR-PCR is developing cheap, highly mobile, and low energy methods for precise detection and rapid diagnosis of new contagions, potentially changing how crises, such as the recent Ebola and Zika outbreaks, would be contained. The team is led by Yossi Weizmann, Assistant Professor, The University of Chicago Physical Sciences Division, and Postdoctoral Scholars Dr. Zoya Cheglakov and Dr. Jung-Hoon Lee"
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